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While internal validity focuses on accuracy within the study cohort, researchers must also consider how well findings apply to outside populations, a concept known as external validity

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Finally, pharmacological targeting of the activity of -glutamyltransferases prevents the breakdown of circulating GSH, reduces tumour cysteine levels and slows tumour growth

Experimental evidence indicates curcumin safely mitigates these effects, reducing cisplatin-induced anxiety and depressive behaviors (Demir et al., 2016)

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