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There were no differences in age, BMI, gender, HDRS-24 scores before treatment, treatment days and other demographic characteristics between the effective-treatment and ineffective-treatment groups, there was significant difference in the reduction rate of HDRS-24 scores and HDRS-24 scores after treatment between the two groups (Table 2)

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[DOI] [PubMed] [Google Scholar] Kelly G.S

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In this pathway, secreted PCSK9 binds to the epidermal growth factor A (EGF-A) domain of LDLR, directing its trafficking from the plasma membrane to the endosomal and then lysosomal compartments (Zhang et al., 2007)