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10.4077/cjp.2016.bae383 33 GoonesekeraS

Perry JJ, Shin DS, Getzoff ED et al (1804) (2010) The structural biochemistry of the superoxide dismutases
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By the time the supplement reaches the small intestine where absorption occurs, the glutathione molecule may no longer be intact

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This phenomenon is mechanistically regulated by negative feedback control mediated by the downstream targets CYP1A1 and AHRR [7, 8]
