glutathione antioxidant mechanism Apoptosis and glutathione: beyond an Understanding mechanisms of antioxidant action
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Even under ideal conditions, it is not completely anhydrous

In wild-type mice given intravitreal iron injections, in vivo imaging and quantitative PCR revealed that merely Fe 2+ induced PR autofluorescence and a raised level of ferroptosis markers, contributing to PR death (106)

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This effect is dose-dependent and duration-dependent, meaning higher doses and prolonged use increase deficiency risk
