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The control of cholesterol and lipid metabolism is sexually dimorphic, and the postmenopausal reduction of circulating estrogens alters liver lipid metabolism, with severe systemic consequences (253)

This converts biologically inactive apo-FDH to active holo-FDH

Additionally, busulfan can decrease Bcl-2 gene expression (as an antiapoptotic gene) and increase Bax gene expression (as a proapoptotic gene) in epididymal sperm of busulfan treated mice, which are related to increased oxidative stress as a result of decreased enzymatic antioxidants of GPx and SOD and increased level of lipid peroxidation in sperm cell (50)

Moreover, this study effectively demonstrated the inferential capacity of the model framework under irradiation and hypoxia conditions

Dietary lipids fuel GPX4-restricted enteritis resembling Crohns disease

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