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However, during high-fat diet (HFD) feeding, obesity and insulin resistance, the accumulation of medium-chain and long-chain acylcarnitines due to incomplete -oxidation may negatively regulate the expression of nuclear-encoded mitochondrial genes, further reducing mitochondrial number and function and creating a vicious metabolic cycle [33]

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Shake or stir the liquid thoroughly to ensure even distribution

doi: 10.1002/ehf2.14228

In particular, doses of 3 to 4 g of l-C or GPL-C ingested between 60 and 90 min before exercise could improve the lactate threshold and achieve lower levels of perceived exertion during incremental tests until exhaustion, as well as increasing peak and average power in the Wingate cycle ergometer test

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