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C.BrookesP

Acetylcholine attenuated TNF-alpha-induced intracellular Ca(2+) overload by inhibiting the formation of the NCX1-TRPC3-IP3R1 complex in human umbilical vein endothelial cells

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Abstract Drug repurposing is a significant strategy in drug discovery, as it saves substantial amounts of time and money

The maximum C1-27 treatment-related weight loss during the course of the study did not exceed 12% (Supplementary Fig

The reactivation of TERT mainly through various mechanisms such as mutations in the chromosomal rearrangements (510%), promoter (3060%) and gene amplification, it results in a re-expression and enhanced activity of TERT, which boosts cell survival and proliferation, and against senescence
