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Brenu EW, van Driel ML, Staines DR, Ashton KJ, Hardcastle SL, Keane J, et al

21,22 Enhanced TJ permeability can result from defective integrity of either barrier-forming or activating pore-forming TJs, also known as leak and pore pathways, respectively
Moreover, response to treatment might be highly heterogeneous

This blog explores how mast cells influence the pathogenesis of autoimmune brain disorders

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