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It's a growth signal that tells cells to multiply and telling cells to grow in an uncontrolled way is a real safety concern
Clinical trials, such as that by Falutz et al

doi: 10.1016/j.tem.2022.08.001

doi: 10.1017/S0031182007004064
10.1016/j.tcb.2015.12.007 335 WannametheeS

Protect your antioxidants: start by improving your sleep routines
