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Amino acid deprivation using enzymes as a targeted therapy for cancer and viral infections

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In murine studies, deletion of the IGF-1R in skeletal muscle resulted in glucose intolerance issues ultimately leading to T2D at an early age, because, although they express insulin receptors, they cannot form hybrid or IGF-1 receptors [162]

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Figure 5 In light of these findings, the association between urinary hyaluronidase activity and the AQP2/creatinine ratio was studied

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