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Oral administration at 100150mg to match subcutaneous bioavailability doubles the per-dose cost, which influences protocol design when budget constraints exist

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Science (2017) 355(6331):132430

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Factors affecting excitatory amino acid release following severe human head injury

Migraines can also manifest as a constellation of other debilitating symptoms, including profound nausea, acute light sensitivity, and in some cases, neurological phenomena known as auras that can disrupt vision and sensation