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As a polyspecific transporter, OCTN1 is capable of transporting a variety of organic cations and zwitterions (e.g., tetraethylammonium, acetylcholine, and ergothioneine) and is also involved in the transport of certain drugs

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Moreover, the production of HNO is dependent on the lipoate-rich PDH complex facilitating irreversible modifications that are critical to NO-dependent metabolic rewiring

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doi: 10.1186/s12866-024-03683-w 66 SilvennoinenJRisteliLKarttunenTRisteliJ