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Introduction Hyperammonaemic encephalopathy (HE) is a condition characterized by dysfunction of the central nervous system due to excessively high levels of ammonia (NH 3 ) in the blood (hyperammonaemia) ( The association between VPA, a widely used AED, and HE has been has been extensively documented in numerous studies, indicating a significant correlation between the two

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To illustrate the dynamic range of the TBARS assay in human serum, a concentration of 2 mM Cu(II) ions was added to the samples, followed by incubation for 24 h at 37 C

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