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Nat Rev Rheumatol (2020) 16(3):14554

112 LiR.LiX.WuH.YangZ.LiF

Concurrently, radiationtriggered sphingomyelinase activation disrupts membrane integrity, synergizing with receptorinteracting protein kinase 3 (RIPK3)/mixed lineage kinase domainlike pseudokinase (MLKL)mediated necroptosis to form an interconnected cell death network [108]

Chen C, Chen J, Wang Y, Fang L, Guo C, Sang T, Wang X (2023b) Ganoderma lucidum polysaccharide inhibits HSC activation and liver fibrosis via targeting inflammation, apoptosis, cell cycle, and ECM-receptor interaction mediated by TGF-/Smad signaling

K.GiridharP.RajasekaranT.RavishankarG

Cell-specific transcriptomics reveal pronounced age-dependent changes in glial gene expression, whereas the neuronal transcriptome shows only minor changes 178,179,180