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These results revealed that Douchi-derived peptides can mediate antioxidant effects in vivo by both scavenging free radicals and activating endogenous antioxidant enzymes.

The current model consists of AS3MT methylating iAs in the presence of the cofactor S-adenosyl-L-methionine (SAM), and the formation of intramolecular disulfide bonds following the reduction of MAsV to MAsIII