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In vivo, 2B3-101 and pegylated liposomal doxorubicin had a comparable plasma exposure in mice, yet brain retention 4 days after administration was higher for 2B3-101

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The researchers hope to move the technology into clinical trials within three years, and note that it could also be used to treat conditions affecting other parts of the body, not just the brain

Lomaestro BM, Malone M