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As acetyl-CoA stores are depleted, the synthesis of NAGA an important cofactor of CPS I from acetyl-CoA and glutamate by NAGA synthetase is decreased

Binding of 4EBP1 to eIF-4E prevents eIF-4E from interaction with the cap structure of mRNAs which is necessary for translational initiation

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[DOI] [PubMed] [Google Scholar] Vidal-Casariego A., Burgos-Pelez R., Martnez-Faedo C., Calvo-Gracia F., Valero-Zanuy M.., Luengo-Prez L.M., Cuerda-Comps C
