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Furthermore, celastrol and shikonin have been identified as inhibitors of the glycolytic enzyme PKM2, which helps alleviate renal damage in SA-AKI (210, 211)

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doi: 10.1017/neu.2019.30

The volcano plot was performed to visualize the predictive component loading and identify significantly altered metabolites by their content variation (Difference) and statistical significance (log 10 P -value)

Notice to US food and drug administration of the conclusion that the intended use of curcumin is generally recognized as safe