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COMT inhibitors reduce metabolism of L-DOPA in the periphery, which increases the effective half life of circulating L-dopa, allowing less frequent dosing
10.1161/ATV.0000000000000172 20 CaoR
Physicians must also consider FDA law and malpractice insurance coverage
The end results of this signaling pathway are defective blood flow, neovascularization, increased vascular permeability, occluded vessels, and a proinflammatory state [14] (Fig
Ceriello A (2000) Oxidative stress and glycemic regulation
