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doi: 10.2174/09298673113209990158

IP3, a small molecule with a powerful message

A similar study was also conducted by Konstantin et al

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However, acetaminophen toxicity has been implicated in a wide range of other disorders in humans and/or experimental animals including cancer, birth defects, asthma, allergies, and brain toxicity (Table 1)

We also determined that the hydrophobic leucine residues in 1907 (L142, L145, L148, L149, and L152) are buried deeper into the FAT domains leucine binding pocket, up to 1.64 closer than seen in the LD2 model, which was an unexpected finding and may explain the increased affinity of 1907