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According to the randomization procedure, Group 1 was assigned to the novel methylcobalamin nasal spray (NASO B12) and Group 2 was assigned to methylcobalamin oral tablet for the treatment of vitamin B12 deficiency during the study period of 15 days [Figure 1]

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Methylation is key to bioavailability

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In addition to fatigue, a deficiency of B12 can lead to other symptoms like pale skin, headaches, depression, gastrointestinal problems, difficulty concentrating, decreased mental function, mouth and tongue pain or inflammation, and paresthesia in your hands and feet