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68 Although the concentration of free copper in cells is almost negligible, it still has a potentially detrimental effect on cell membranes, proteins, and nucleic acids

Caffeine consumption requires thoughtful management

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Besides, conjugation of INH with vitamin B6 (pyridoxal and pyridoxal 5-phosphate) leads to the depletion of pyridoxal 5-phosphate in both humans and lab animals61, 136, INH has also been found to reduce the plasma concentrations of calcium and phosphate ions