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The spirosuccinimide of ( S )-dHTC1 engages the IMiD-binding site of CRBN but, interestingly, it adopts a slightly different pose in the ternary complex compared to what was revealed by the co-crystal structure of the binary complex (Extended Data Fig

N -acetylcysteine reduces disease activity by blocking mammalian target of rapamycin in T cells from systemic lupus erythematosus patients: a randomized, double-blind, placebo-controlled trial

Aurothioglucose had a less inhibitory effect on the reduction of GSSG and Grx activity (HED-coupled assay) than on the reduction of DTNB, whereas the other two gold compounds inhibited to a similar extent all three principal activities of TGR (Table 4)

Ascorbate as a co-factor for Fe-and 2-oxoglutarate dependent dioxygenases: physiological activity in tumor growth and progression

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