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Each of these points reflects findings from the experimental literature rather than approved indications

Reviewed by Natalie Punt, DVM This article was reviewed by Natalie Punt, DVM

Duplex ultrasonography is the preferred investigation to demonstrate reflux and communications between the deep and superficial venous networks

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When this barrier becomes compromised, a condition often referred to as leaky gut may develop

Their core value lies in synergizing with conventional treatments to enhance efficacy and reduce adverse effects, addressing unmet needs in ADs such as long-term remission maintenance and slowing early disease progression, without replacing core first-line therapies