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Funding This work has been supported by the Key Project of Natural Science Research of Universities in Anhui Province (2022AH051190), the Open Fund of Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, P.R

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Reviewer information Nature thanks Christian Siebold, Ieva Sutkeviciute, Jean-Pierre Vilardaga and the other anonymous reviewer(s) for their contribution to the peer review of this work

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