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Castell L, Vance C, Abbott R, Marquez J, Eggleton P

403,404 The PHERGain study explored whether it is possible to treat patients with early HER2+ breast cancer with dual antibody therapy alone in both neoadjuvant and adjuvant settings, completely sparing chemotherapy

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While iron homeostasis is an important contributor to IR-induced ferroptosis in all cells, few studies have explored the relationship between IR, ferroptosis, and dietary iron absorption and metabolism in the intestine

153 Noise can damage cochlear tissues through a variety of mechanisms that are also factors in age-related hearing loss, such as increased inflammation and free radical production, disordered calcium metabolism in the inner ear, altered cell signaling, and programmed cell death, all of which have been implicated in hair cell and auditory neuron damage

Women of childbearing age should use contraception while on tirzepatide and discontinue the medication at least 2 months before attempting conception to allow complete washout given the long half-life