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Their findings were striking: AKD patients treated with GLP-1 RAs experienced lower rates of major adverse kidney events (MAKEs), which include complications like the need for dialysis, worsening kidney function, and even death due to kidney failure

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37 Given the promising results of semaglutide 2.4 mg, the phase 3b STEP-UP trial compared intensified semaglutide 7.2 mg with semaglutide 2.4 mg in adult patients with a BMI of 30 kg/m 2 and above, without diabetes

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They found that the contaminant appeared able to inhibit the secretion of gastric acid (Brown, Magee)