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Tirzepatide requires higher absolute milligram doses because its binding affinity and receptor activation profile differ from semaglutide

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The systematic review makes this clear: BPC-157 has almost no human evidence supporting clinical use (Park, 2025)

Cette signature "bidirectionnelle" reste toutefois difficile a valider avec la methodologie moderne et doit etre consideree comme une hypothese de travail, pas un fait etabli
