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The relationship between TNF- and spike protein was monitored in both treated and untreated PBMCs

Eur J Anaesthesiol 26:128134

Effect of the NAD(P)H oxidase inhibitor, apocynin, on peripheral nerve perfusion and function in diabetic rats

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It appears that SARS-CoV-2 may induce comparable changes in these pathways but, to date, it is not known whether low Se status modulates the effect of the virus on such pathways and so enhances the cytokine storm observed in severe cases of COVID-19

10.1016/j.bbamem.2004.09.007 88 OppedisanoF.PochiniL.GalluccioM.IndiveriC