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After the rest phase, the cycle can be repeated
Given that many PD-associated proteins regulate mitochondrial health, oxidative stress, and iron homeostasis, their dysregulation provides a direct mechanistic bridge to ferroptosis in PD progression ( Figure 3 )
10.1042/BJ20112131 Biochem
This condition results in the formation of CaOX crystals, which gradually accumulate in the renal interstitium or collecting ducts, eventually causing nephrocalcinosis [11]
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Fourier transform spectroscopy
