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Funding This work was supported by the CNPq/Brazil, Bill & Melinda Gates Foundation (process 401726/2015-0 APP/Call 47/2014) and the INCT/Excitotoxicity and Neuroprotection (465671/2014-4)

Food and Nutrition: Vitamin B12

The evidence base for use of these drugs, either for off-label indications or as non-approved drugs, is wanting

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But at the same time, the evidence behind the link between B12 and sleep isnt completely clear

Similar results were obtained for two other human albumin fusion designs, where either recombinant coagulation factor IX (FIX) 9 or angiotensin-converting enzyme 2 (ACE2) 13 was genetically fused to the N-terminal end of human albumin (Supplementary Fig