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A Systematic Review and Meta-Analysis Evaluating the Efficacy of Stand-Alone Digital Interventions to Prevent Substance Use Among Adolescents

It sets a reference for other countries

A correlation is apparent between these factors, but it is difficult to clearly determine its direction

Halbeisen et al., 2018)

The idea that a leaky gut can cause problems outside the intestine relies on the hypothesis that microbial products in the intestine are able to escape the gut and elicit an inflammatory reaction wherever they may end up. Chung, Patel and colleagues took a two-pronged approach in their study: a meta-analysis of the existing literature to compare the rates of increased intestinal permeability in patients with or without NAFLD, and in vitro and in vivo experiments to explore the underlying mechanisms that contribute to this change in intestinal permeability

Ultrasound imaging and BBB opening experiments validated the ability of LIFU-mediated Curcumin-PLGA nanoparticles to effectively deliver curcumin into deep brain regions
