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Eur J Clin Pharmacol 26, 1984

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Appropriate caution should be exercised while treating severe megaloblastic anemia with cyanocobalamin as intense treatment may lead to hypokalemia and sudden death

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Symptoms of vitamin B12 deficiency Some of the symptoms that can be caused by a lack of vitamin B12 include: Poor appetite Anemia Fatigue Weakness Numbness or tingling in the hands or feet Difficulty with balance Vitamin B12 deficiency can also contribute to depression, cognitive impairment, and dementia

Cdkn2a transcripts were rarely detected, in agreement with previous observations in the Tabular Muris Senis project 8 , and primarily observed in the MuSCs and progenitors and cycling T cells