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Sin embargo, las concentraciones elevadas de TMAO en la sangre pueden ser un biomarcador de la enfermedad ms que un factor causante (120, 121)
However, most of these methods require either precolumn or postcolumn derivatization of GSH with fluorescent (monobromobimane, o-phthalaldehyde), and chromophoric (N-ethylmaleimide or iodoacetic acid) agents or reduction with reducing agents [Citation57], which often rely on time-consuming protocols and are prone to the loss of sensitivity in each derivatization step
