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As noted above, the incorporation of modified nucleosides like pseudouridine and 5-methylcytidine in place of uridine can mask the mRNA from TLRs and RIG-I, dramatically lowering interferon activation [2]
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Nair G, Dodd S, Ha S-K, Koretsky AP, Reich DS
Collier, TCU
Polyphenolic compounds such as resveratrol and quercetin exert renal protective effects through activation of multiple pathways including Nrf2, AMPK, and SIRT1 (302)
