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Statistical analyses The target sample size was calculated as follows

For more exploration of the angiogenesis issue, see the article that we have published on potential complications of TB-500

Since then its been studied extensively for its effects on gene expression influencing thousands of genes related to collagen production, tissue remodeling, antioxidant protection, and inflammation control

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Furthermore, it plays an important role in tumor progression by regulating methyl donor metabolism and participating in multiple signaling pathways