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In addition, novel regulators such as RNA methylation enzymes (METTL3/14) that modulate GPX4 mRNA stability (176), or RhoA-mediated vascular remodeling that enhances iron leakage into subchondral bone (97), may offer new molecular targets

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The findings may suggest that these remedies may be used as potential therapeutic targets for HT treatment

Offenbaecher M., Bondy B., Jonge S
These were randomized, controlled trials in healthy adults
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