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Botham, PhD, DSc & Peter A

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doi:10.1523/JNEUROSCI.2637-08.2008 pmid:18799684 Kuhn C, Johnson M, Thomae A, Luo B, Simon SA, Zhou G, Walker QD (2010) The emergence of gonadal hormone influences on dopaminergic function during puberty

In cultured pulmonary endothelial cells in vitro, carnitine can effectively reduce the apoptosis, damage to migration and obstruction of angiogenesis caused by hyperoxia, resulting in improvements in endothelial cell dysfunction and persistent lung injury under hyperoxic conditions [308]

By inhibiting oxidative phosphorylation (OXPHOS), which induces mitochondrial hyperpolarization and subsequently stimulates ROS production [23], the oxidation of palmitoylcarnitine (C16-carnitine) produces more ROS in mitochondria than carbohydrates [24]