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Steric hindrance is the major limiting factor in the synthesis of the B 12 coenzyme analogs

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Injection site reactions typically clear within 2 to 3 days

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Most people in the general population can get enough vitamin B12 from a balanced diet

In the UK, B12 injectionstypically hydroxocobalaminare prescribed through the NHS for documented deficiency states such as pernicious anaemia or malabsorption disorders