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Generation of iPSC-derived kidney organoids recapitulating human Fabry nephropathy To generate Fabry kidney organoids, GLA-mutant human iPSCs were differentiated into kidney organoids using an adherent cell culture protocol 15,16

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In the last decade, the clinical burden of NAFLD has been associated to liver-related morbidity and mortality and also to the extra-hepatic manifestations involving other organs and regulatory pathways

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Pain behavior was quantified periodically at 5- and 35- min intervals (representative values of phases 1 and 2) by counting the number of flinches exhibited by the injected paw after injection