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L-carnitine is the predominant carnitine used in biological and medical fields and is commonly referred to as carnitine. The human body contains about 300 mg/kg of L-carnitine, 98% of which is intracellular, with 80% present in the muscles, 510% in the gastrointestinal tract, and 3% in the liver (11)

Table 3 Summary of the concepts regarding digitalizing MS fatigue assessment and therapy

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Knockdown of CrAT or CrOT decreased histone acetylation (Extended Data Fig