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Rusolo et al
With respect to cell death, induction of p21 FL modestly delayed the onset of erastin2-induced death alone, and to a greater extent when combined with nutlin-3, consistent with an independent requirement for both p53 and p21 in the suppression of ferroptosis (Fig 2F)
Deoxynivalenol (DON) is a Fusarium toxin that promotes hepatocyte ferroptosis and causes liver injury by modulating the Nrf2/PPAR-GPX4 pathway
Selenium is a trace mineral needed by all mammals to sustain life
21st century life challenges our ability to keep optimal glutathione levels
CA Cancer J Clin (2016) 66(2):11532
