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These may include headaches, nausea, injection site reactions since its administered via a subcutaneous injection, water retention, and altered cortisol levels

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Brown RM, Kupchik YM, Kalivas PW

Six mild to moderate adverse events occurred during the study, but no serious events were reported

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Despite decades of research, DSIP remains somewhat enigmatic it has been studied for diverse effects including sleep regulation, stress adaptation, pain modulation, neuroendocrine function, and even potential antitumor properties, yet its precise mechanisms, endogenous functions, and therapeutic potential continue to be subjects of scientific debate and investigation