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Splenectomy may be considered for patients with massive splenomegaly causing discomfort, hypersplenism resulting in excessive red cell destruction, or rising transfusion needs
J Neurochem 52: 17811786
doi: 10.1080/15384101.2015.1120930
(PubMed) Wu X, Yang K, Tang X, et al
Cancer Res (1992) 52(7):17449
Following dosing, the ARA 290 group increased their walk distance by a mean of 3.5% of baseline ( p = 0.09), whereas the placebo group increased walk distance by 1.1 % of baseline ( p = ns [not significant])
