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Description
The safety data for each compound individually is reassuring, but combination safety requires its own evaluation because pharmacological interactions can produce unexpected results even when each agent is well-characterized on its own
Importantly, NNMTi is highly selective and has no inhibitory effect on other SAM-dependent methyltransferases or NAD + salvage pathway enzymes
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Importantly, the study confirmed that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo, with no treatment-related serious adverse events or study withdrawals occurring
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Use must comply with all applicable laws and regulations.
