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If the solution appears cloudy, discolored, or contains particles that do not dissolve after 10 minutes of gentle rolling, something has gone wrong

This is driven by the likelihood of subchondral bone changes as a consequence of failed repair, particularly if the first attempt involved disruption of the tidemark for marrow recruitment

Just wondering - if not oil, what is it in Depot injection that gives slower release into the blood - polymers

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However, there was an unusual pattern: creatinine rose without a corresponding increase in blood urea nitrogen (BUN)

Some such as PRP injections are already available and used regularly in my clinic