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This study demonstrated that wireless optogenetics can be used to stimulate the ENS and increase colonic transit in conscious, freely moving animals

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Overall, Wld s mouse studies largely show the neuro protective function of the biosynthetic enzymes NMNAT1, NMNAT2 and NMNAT3 (REFS 142,150152 ) and their protective role in several neurodegenerative disorders, including Parkinson disease 153155

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This deficit in mitochondrial energy reserve is well-documented in clinical literature [1]