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Although it has been proposed as an effective biomarker, only EoPE (but not LoPE) is associated with increased PAI-1/PAI-2 ratio [75]

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For external use only

Table I [i] ROS reactive oxygen species, O 2 superoxide radical, mtDNA mitochondrial DNA, 8OHdG 8-hydroxy-2-deoxyguanosine, UCP2 uncoupling protein 2, CYP2E1 cytochrome P450 2E1, NOX NADPH oxidase, MDA malondialdehyde, 4-HNE 4-hydroxynonenal, TGF- transforming growth factor-, H 2 O 2 hydrogen peroxide

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Protection against ischemic brain injury by protein therapeutics