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In macrophages, dendritic cells (DCs), and natural killer (NK) cells, TLR activation promotes intracellular NF-B phosphorylation and nuclear translocation, enhancing antigen presentation, phagocytosis and the production of various pro-inflammatory cytokines, such as IL-1, IL-6, TNF-, IFN-, and IL-18 (76, 77)

Antioxidants like carotenoids protect the skin against UV damage

Discovery of indenopyrazoles as a new class of hypoxia inducible factor (HIF)-1 inhibitors

Evaluation of acute toxicity and the effect of single injected doses of zerumbone on the kidney and liver functions in Sprague Dawley rats

CONCLUSIONS Cats are deficient in a number of drug conjugation pathways that can lead to relatively slow elimination of certain drugs, and the need for dose adjustment or alternative therapies to avoid serious adverse effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 287.Cicik E., Tekin H., Akar S., Ekmekci O.B., Donma O., Koldas L., Ozkan S