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However, silybin, EGCG, myricetin, baicalein, curcumin, and quercetin significantly changed AUC 0- and the metabolite-maternal ratio (MR) of 4- hydroxy-tamoxifen, indicating that it can significantly increase the bioavailability of TAM and affect the formation of 4-hydroxy-tamoxifen (Table 1

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Conlon et al, 2021) (Fig 5C)

14,22 Dysbiosis, or imbalance in the composition and/or function of this microbial community, has been strongly associated with GI diseases 6 as well as systemic conditions via its influence on other organs through the numerous gut-organ axesemphasizing the gut's interconnectedness with broader health processes

[DOI] [PMC free article] [PubMed] [Google Scholar] Melis MR, Succu S, Argiolas A (1996) Dopamine agonists increase nitric oxide production in the paraventricular nucleus of the hypothalamus: correlation with penile erection and yawning